One Health – antimicrobial stewardship in human and veterinary medicine
Team leader – Małgorzata Olejnik, PhD
Antimicrobial resistance (AMR) is one of the biggest challenges in healthcare in 21st century. Assuming the current trends continue, it could cost even 10 million lives a year already in 2050. Around 50% of antimicrobials are used unnecessarily in both human and veterinary medicine. It is therefore necessary to act holistically and reduce antimicrobial use for treatment of people and animals, according to One Health initiative.
The evidence-based medicine needs reliable data:, the susceptibility of local pathogens, pharmacokinetic profiles of antimicrobials, the influence of therapies on microbiome or end-points to end treatment, etc. Our team including microbiologists, pharmacologists, molecular biologists, and clinicians will provide some of that data. The team will exchange good practices and integrate research to include both human and veterinary medicine perspectives.
The research will be organized within the following areas:
- AMR surveillance (leader: dr Katarzyna Grudlewska-Buda, Faculty of Pharmacy);
- PK/PD of antimicrobials (leader: dr hab. Małgorzata Olejnik, Faculty of Biological and Veterinary Sciences);
- Animal Microbiome (leader: dr hab. Anna Sławińska, Faculty of Biological and Veterinary Sciences);
- Antimicrobial stewardship in practice (leader: dr hab. Aleksander Deptuła, Faculty of Pharmacy).
Dr. hab. Małgorzata Olejnik works at the Department of Basic and Preclinical Sciences of the Faculty of Biological and Veterinary Sciences of the Nicolaus Copernicus University. In 2005, she graduated from pharmacy at the Medical University of Lublin and began doctoral studies at National Veterinary Research Institute in Pulawy, where she obtained a doctoral degree in veterinary sciences in 2009. In 2010-2012, she completed a postdoctoral internship at the Laboratoire d’Etude des Residues et Contaminants dans les Aliments in Nantes (France). She received her habilitation degree in 2016. In 2020, she was employed at the Nicolaus Copernicus University as associate professor.
Dr. hab. Małgorzata Olejnik is a researcher in veterinary pharmacology and toxicology. Her interests include in particular antimicrobial drugs and coccidiostats. She was the principal investigator, contractor and scientific supervisor in projects funded by National Science Centre and Ministry of Science and Higher Education. Currently, she is a principal investigator in two projects funded by the National Science Centre: “Mechanism of salinomycin toxicity – the reasons for the differences in chickens’ and turkeys’ species susceptibility” (SONATA BIS 10) and “Hazards related to cross-contamination of feed with antibiotics” (OPUS 21). She participates in the COST action European Network for Optimization of Veterinary Antimicrobial Treatment (ENOVAT). She also has extensive organizational experience. She managed the work package of the VET-TWIN twinning project under the Horizon 2020. She was a co-author of NVRI restructuring program, which resulted in the creation of a core facility carrying out omics research.